Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis.
Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101.
The Formation of a Camalexin Biosynthetic Metabolon.
The Formation of a Camalexin Biosynthetic Metabolon.
Plant microbiota feedbacks through dose-responsive expression of general non-self response genes.
Minimum set of cytochromes P450 for reconstituting the biosynthesis of camalexin, a major Arabidopsis antibiotic.
-
Recombinant CYP71A12 turns over IAOx at a rate comparable to CYP71A13 via an alpha-hydroxy-IAN intermediate but yields mostly indole-3-carbaldehyde rather than the camalexin-bound Cys-IAN adduct.
"Conversion to oxidized products at the assay endpoint is illustrative: CYP71A13 produced Cys-IAN (20%) and IAL (2%), while CYP71A12 produced Cys-IAN (3%) and IAL (18%)."
TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines.
-
CYP71A12 is the major enzyme for inducible indole-3-carboxylic acid (ICOOH) biosynthesis and a minor contributor to leaf camalexin.
"A major role of CYP71A12 was identified for the inducible biosynthesis of ICOOH ."
A new cyanogenic metabolite in Arabidopsis required for inducible pathogen defence.
-
CYP71A12 (not CYP71A13 or CYP71A18) is required for ICN/4-OH-ICN pathway metabolites, and cyp71A12 leaves are more susceptible to Pst.
"all ICN derivatives with the exception of A6 are at ~10% of WT levels in the cyp71A12 mutant, but unaffected in the cyp71A13 and cyp71A18 mutants"
Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns.
-
Flg22-induced root camalexin depends on CYP71A12.
"Indeed, a cyp71A12 insertion mutant was dramatically impaired for camalexin accumulation in the roots ( Figure 3 )."
De novo genetic engineering of the camalexin biosynthetic pathway.
Dissection of the network of indolic defence compounds in Arabidopsis thaliana by multiple mutant analysis.
Cell-type-specific responses to fungal infection in plants revealed by single-cell transcriptomics.
The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity.
-
CYP71A12, but not CYP71A13, is the major enzyme for pathogen-induced ICA accumulation; cyp71A12 contributes to post-invasion resistance to filamentous fungi.
"Our results indicate that CYP71A12, but not CYP71A13, is the major enzyme responsible for the accumulation of ICA in Arabidopsis in response to pathogen ingression."
The Biosynthetic Pathway of Indole-3-Carbaldehyde and Indole-3-Carboxylic Acid Derivatives in Arabidopsis.
CYP71A12 deep research (falcon)
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis.