PANTHER PTHR47992 PP2C/clade A phosphatase family context
PANTHER PTHR47992 PP2C/clade A phosphatase family context
Falcon deep research report for Arabidopsis ABI1
UniProtKB record for Arabidopsis ABI1
Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
The role of ABI1 in abscisic acid signal transduction: from gene to cell.
Role of Abscisic Acid in Drought-Induced Freezing Tolerance, Cold Acclimation, and Accumulation of LT178 and RAB18 Proteins in Arabidopsis thaliana.
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The abi1 and aba-1 mutants have impaired induced freezing tolerance in this study.
"ABA appears to be involved in both LT- and drought-induced freezing tolerance, since both ABA mutants were impaired in their responses to these stimuli."
Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance.
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abi1 has impaired acquired thermotolerance.
"Abscisic acid (ABA) signaling mutants (abi1 and abi2) and the UV-sensitive mutant, uvh6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival."
The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis.
A bifurcating pathway directs abscisic acid effects on stomatal closure and opening in Arabidopsis.
The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.
Nuclear localization of the mutant protein phosphatase abi1 is required for insensitivity towards ABA responses in Arabidopsis.
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Nuclear ABI1 accumulation is associated with enhanced inhibition of ABA responses.
"Application of a proteosomal inhibitor led to both a preferential nuclear accumulation of ABI1 and an enhancement of PP2C-dependent inhibitory action on the ABA response."
Cold acclimation and cold-regulated gene expression in ABA mutants of Arabidopsis thaliana.
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Cold-induced cor expression was largely preserved in abi1; this abstract does not establish the annotated cold-response defect.
"Cold-regulated expression of all three cor genes, however, was nearly the same in wild-type and abi1 mutant plants."
F-box protein DOR functions as a novel inhibitory factor for abscisic acid-induced stomatal closure under drought stress in Arabidopsis,
Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.
Regulators of PP2C phosphatase activity function as abscisic acid sensors.
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ABA receptor RCAR1 inhibits ABI1 and ABI2.
"RCAR1 was shown to bind ABA, to mediate ABA-dependent inactivation of ABI1 or ABI2 in vitro, and to antagonize PP2C action in planta."
Closely related receptor complexes differ in their ABA selectivity and sensitivity.
Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis.
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Group A PP2Cs inhibit SnRK2 kinases by activation-loop dephosphorylation.
"Group A PP2Cs interacted physically with SnRK2s in various combinations, and efficiently inactivated ABA-activated SnRK2s via dephosphorylation of multiple Ser/Thr residues in the activation loop."
Structural basis of abscisic acid signalling.
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The ABA-PYL1-ABI1 complex structurally explains phosphatase inhibition.
"(+)-ABA-bound PYL1 tightly interacts with a PP2C domain of ABI1 by using the hydrophobic pocket to cover the active site of ABI1 like a plug."
PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.
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ABI1 associates with three ABA-responsive SnRK2 kinases in planta.
"We confirm previous studies in yeast and now show that ABI1 interacts with the ABA-signalling kinases OST1, SnRK2.2 and SnRK2.3 in plants."
Structural insights into the mechanism of abscisic acid signaling by PYL proteins.
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ABA-bound PYL1 occludes the ABI1 active site.
"In the ternary complex, the CL2 loop is located near the active site of ABI1, blocking the entry of substrate proteins."
A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.
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PYR1 and PYL1-6 were tested for interaction with ABI1 as well as other PP2Cs.
"Each of these family members was capable of interacting with the ABA-signaling PP2Cs HAB1, ABI1, and ABI2"
In vitro reconstitution of an abscisic acid signalling pathway.
Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair.
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ABI1 binds OST1 in the guard-cell channel regulatory system.
"Using split YFP assays, we identified OST1 as an interaction partner of SLAC1 and ABI1."
A protein kinase-phosphatase pair interacts with an ion channel to regulate ABA signaling in plant guard cells.
Guard cell anion channel SLAC1 is regulated by CDPK protein kinases with distinct Ca2+ affinities.
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ABI1 suppresses CPK-dependent SLAC1 activation; the abstract alone does not resolve the direct kinase-binding assay.
"In line with activation by OST1, CPK activation of the guard cell anion channel was suppressed by ABI1."
Identification and mechanism of ABA receptor antagonism.
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The PYL1-pyrabactin-ABI1 complex supports receptor interaction.
"Crystal structures of the PYL2-pyrabactin and PYL1-pyrabactin-ABI1 complexes reveal the mechanism responsible for receptor-selective activation and inhibition"
Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco.
The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins.
Evidence for network evolution in an Arabidopsis interactome map.
Molecular mechanism for inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by protein phosphatase ABI1.
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ABI1 recognizes the SnRK2.6 activation loop for dephosphorylation.
"Structural modeling suggested that the two interfaces lock SnRK2.6 and ABI1 in an orientation such that the activation loop of SnRK2.6 is posited to the catalytic site of ABI1 for dephosphorylation."
Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13.
ABI1 and PP2CA phosphatases are negative regulators of Snf1-related protein kinase1 signaling in Arabidopsis.
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ABI1 and PP2CA couple ABA and energy signaling by inhibiting SnRK1.
"two clade A type 2C protein phosphatases (PP2Cs), established repressors of the abscisic acid (ABA) hormonal pathway, interact with the SnRK1 catalytic subunit causing its dephosphorylation and inactivation."
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ABI1 binds the SnRK1.1 regulatory domain, supporting kinase recognition.
"SnRK1.1 interacted with ABI1 and PP2CA in yeast cells, and deletion of its regulatory domain (RD) abolished this interaction"
An abscisic acid inducible Arabidopsis MAPKKK, MAPKKK18 regulates leaf senescence via its kinase activity.
Arabidopsis ABA-Activated Kinase MAPKKK18 is Regulated by Protein Phosphatase 2C ABI1 and the Ubiquitin-Proteasome Pathway.
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ABI1 interacts with and inhibits MKKK18.
"Notably, we identified abscisic acid insensitive 1 (ABI1) PP2C as a MKKK18-interacting protein, and demonstrated that ABI1 inhibited its activity."
Release of GTP Exchange Factor Mediated Down-Regulation of Abscisic Acid Signal Transduction through ABA-Induced Rapid Degradation of RopGEFs.
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ABI1 directly interacts with RopGEF1.
"RopGEF1 directly interacts with several clade A PP2C protein phosphatases, including ABI1."
Arabidopsis thaliana RECEPTOR DEAD KINASE1 Functions as a Positive Regulator in Plant Responses to ABA.
CARK1 mediates ABA signaling by phosphorylation of ABA receptors.
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RCAR3 phosphorylation strengthens binding to ABI1.
"Surface plasmon resonance (SPR) assay further demonstrated the phosphorylation of RCAR3 by CARK1 could distinctly enhance its interaction with ABI1 in vitro."
A point-to-point protein-protein interaction assay reveals the signaling interplays among plant hormones and environmental cues.
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JAZ1-ABI1 interaction contributes to hormone signaling cross-talk.
"we next revealed the signaling cross talk between jasmonate and abscisic acid by characterizing the JAZ1-PYL4 and JAZ1-ABI1 interactions."
Extensive signal integration by the phytohormone protein network.
Arabidopsis ABA response gene ABI1: features of a calcium-modulated protein phosphatase.
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An early sequence analysis proposed an EF-hand calcium-binding site; this was not a direct calcium-binding assay.
"the ABI1 protein has a unique amino-terminal extension containing an EF hand calcium-binding site."
A protein phosphatase 2C involved in ABA signal transduction in Arabidopsis thaliana.
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The original cloning paper proposed a putative calcium-binding site from sequence.
"The ABI1 gene encodes a protein with high similarity to protein serine or threonine phosphatases of type 2C with the novel feature of a putative Ca2+ binding site."
Abscisic acid-insensitive mutations provide evidence for stage-specific signal pathways regulating expression of an Arabidopsis late embryogenesis-abundant (lea) gene.
Protein phosphatase activity of abscisic acid insensitive 1 (ABI1) protein from Arabidopsis thaliana.
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ABI1 has Mg/Mn-dependent PP2C catalytic activity.
"recombinant proteins that contained the ABI1 C-terminal domain displayed in vitro phosphatase activity towards 32P-labelled casein, and this activity displayed Mg2+ or Mn2+ dependence and okadaic acid insensitivity typical of protein phosphatases 2C."
ABI1 of Arabidopsis is a protein serine/threonine phosphatase highly regulated by the proton and magnesium ion concentration.
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ABI1 is a magnesium-sensitive protein serine/threonine phosphatase.
"The ABI1 protein (ABI1p) has been characterized as a protein serine/threonine phosphatase of type 2C that is highly affected in its activity by changes in the proton and magnesium ion concentrations."
Protein phosphatase 2C (PP2C) function in higher plants.