Divergent structure and regulatory mechanism of proline catabolic systems: characterization of the putAP proline catabolic operon of Pseudomonas aeruginosa PAO1 and its regulation by PruR, an AraC/XylS family protein.
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A putP knockout grows poorly on proline; PutP is the major proline transporter for proline utilization.
"Thus, PA0781 appears to be irrelevant to proline utilization and PutP PAO is the major proline transporter for proline utilization in strain PAO1, as it is in enteric bacteria"
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PutP of PAO1 is 77-84% identical to PutP of other pseudomonads and E. coli.
"PutP PAO is highly homologous to the PutP proteins of P. fluorescens (84% identity), P. putida (80% identity), and E. coli (77% identity)."
UniProt entry Q9I5F5
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PutP belongs to the sodium:solute symporter family (TC 2.A.21).
"Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family."
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PutP catalyses sodium-dependent uptake of extracellular L-proline.
"Catalyzes the sodium-dependent uptake of extracellular L- proline."
Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic assignment of GO terms using logical inference, based on on inter-ontology links.
Combined Automated Annotation using Multiple IEA Methods