Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
CRTAP is required for prolyl 3-hydroxylation and mutations cause recessive osteogenesis imperfecta.
Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex.
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CRTAP, P3H1 and cyclophilin B form the ER collagen prolyl 3-hydroxylation complex that 3-hydroxylates Pro986 of alpha1(I)/alpha1(II) chains; CRTAP and P3H1 are mutually stabilized, and the complex also acts as a chaperone.
Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex.
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen
Procollagen triple helix formation
Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates
P3HB binds 4-Hyp-collagen propeptides