ALDH3A1 (human, P30838) review notes
- Deep research: no provider deep-research file is available (no API keys in this session); the review
rests on UniProt P30838, the cached literature and Reactome.
- Core: cytosolic NAD(P)+ aldehyde dehydrogenase for medium-chain and aromatic aldehydes
PMID:12943535;
corneal crystallin and UV absorber
PMID:17158879.
- CoQ: in the ubiquinone module only as a rescuer of yeast hfd1
PMID:27693056.
This is heterologous capacity, not evidence of a role in human CoQ biosynthesis, so no ubiquinone or
4-hydroxybenzaldehyde dehydrogenase term is proposed; raised as a suggested question and experiment.
- Membrane (IBA and Compara) marked over-annotated: the ALDH3 node's membrane term comes from anchored
ALDH3A2/HFD1, and ALDH3A1 has no anchor. 3-chloroallyl aldehyde dehydrogenase (IBA) marked over-annotated.
- Bare protein-binding rows (BiFC POT1, HuRI Y2H) removed per policy.