Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes.
Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1.
A reference map of the human binary protein interactome.
FTSJ1 regulates tRNA 2'-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression.
Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs.
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Human-cell FTSJ1 knockout reduces Um32 in tRNAArg(CCG); this experiment establishes cellular dependence without reconstituting an isolated uridine 32 methylation reaction.
"5 tRNAs among the 7 G37‐tRNAs had significantly decreased Ym32 quantity (Y=C, U)"
The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance.
FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe)
FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe)
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation.
A splice site mutation in the methyltransferase gene FTSJ1 in Xp11.23 is associated with non-syndromic mental retardation in a large Belgian family (MRX9).
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The DNA sequence of the human X chromosome.
A loss-of-function mutation in the FTSJ1 gene causes nonsyndromic X-linked mental retardation in a Japanese family.
Positive association of the FTSJ1 gene polymorphisms with nonsyndromic X-linked mental retardation in young Chinese male subjects.
A quantitative atlas of mitotic phosphorylation.
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Genetic variations in FTSJ1 influence cognitive ability in young males in the Chinese Han population.
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Initial characterization of the human central proteome.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.
Correction: FTSJ1 regulates tRNA 2'-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression.
Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.
Structural insights into tRNA recognition of the human FTSJ1-THADA complex.
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The human FTSJ1-THADA activity readout uses an AHCY-coupled fluorescence assay; the C32 structural placement and biochemical turnover measurements are distinct evidence layers.
"SAH produced by the methyltransferase activity of FTSJ1 was degraded to adenosine and homocysteine"
tRNA modification in the nucleus and cytosol
UniProt reviewed Q9UET6 FTSJ1 record
FTSJ1 original source contexts, genuine native mapping and evidence scope