GID1C (At5g27320, UniProt Q940G6) curation notes

Identity

• UniProt Q940G6 GID1C_ARATH "Gibberellin receptor GID1C"; synonyms CXE19, GID1L3; At5g27320. PANTHER PTHR23024:SF492.

Key findings (with provenance)

• GA binding / GA receptor activity of all three AtGID1s [PMID:16709201 "The GA-binding activities of the three recombinant proteins were confirmed by an in vitro assay"; "These results demonstrate that all three AtGID1s functioned as GA receptors in Arabidopsis"].
• gid1a gid1c is the only dwarf double mutant PMID:17521411.
• Low affinity of GID1C for RGL2 explains failure in stamen development PMID:19500306.
• GID1C expressed in valves and style; gid1a gid1c defective in pod elongation PMID:24961590.
• GID1ac clade required for germination PMID:21778177.
• Proteolysis-independent DELLA inhibition by GID1 overexpression in sly1 PMID:18827182.
• Falcon deep research for GID1C timed out (not available).

Curation decisions

• Same scheme as GID1B: hydrolase REMOVE; NOT response to gibberellin REMOVE (redundancy, contradicted); IGI response to gibberellin with GID1A ACCEPT (validator warns about mixed actions on GO:0009739 because negated and positive rows differ - intentional).
• Core: gibberellin binding (GO:0010331), GA mediated signaling pathway (GO:0010476), nucleus.