Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Muscle structure and innervation are affected by loss of Dorsal in the fruit fly, Drosophila melanogaster.

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.

Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells.

Cactin, a conserved protein that interacts with the Drosophila IkappaB protein cactus and modulates its function.

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila.

Sequential activation of signaling pathways during innate immune responses in Drosophila.

Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila.

Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo.

Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology.

cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos.

β-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development.

The IRAK homolog Pelle is the functional counterpart of IκB kinase in the Drosophila Toll pathway.

A genome-wide resource for the analysis of protein localisation in Drosophila.

The Friend of GATA Transcriptional Co-Regulator, U-Shaped, Is a Downstream Antagonist of Dorsal-Driven Prohemocyte Differentiation in Drosophila.

The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity.

A Toll-dependent Bre1/Rad6-cact feedback loop in controlling host innate immune response.

Interactions of a Rel protein with its inhibitor.

Cactus protein degradation mediates Drosophila dorsal-ventral signaling.

Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal.

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila.

An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila.

CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex'

DL/DIF dimer binds to TUB and phosphorylated PLL in TL:MYD88:TUB:PLL 'signalling complex'

CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT is degraded in the cytosol

DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Falcon deep research report for cact

UniProt entry Q03017 (cact)

FlyBase gene description for cact (DROME)