Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB Subcellular Location vocabulary mapping
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs by Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
The human genome has only one functional hsp47 gene (CBP2) and a pseudogene (pshsp47).
Cloning of a human collagen-binding protein, and its homology with rat gp46, chick hsp47 and mouse J6 proteins.
Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells.
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Isolation, characterization and chromosomal assignment of human colligin-2 gene (CBP2).
Collagen biosynthesis and modifying enzymes
Collagen biosynthesis pathway
UniProt entry P50454 (SERPH_HUMAN), Serpin H1 / HSP47
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HSP47 binds specifically to collagen and acts as a chaperone in collagen biosynthesis; it resides in the ER lumen, is heat-shock inducible, belongs to the serpin family (non-inhibitory), and its loss causes osteogenesis imperfecta type 10.