GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10907721
Specific localization of the guanosine triphosphate (GTP) cyclohydrolase I-immunoreactivity in the human brain.
PMID:11943812
A role for alpha-synuclein in the regulation of dopamine biosynthesis.
PMID:12113410
Association between tyrosine hydroxylase polymorphisms and left ventricular structure in young normotensive men.
PMID:12457228
Ultrastructural localization of tyrosine hydroxylase in human peripheral blood mononuclear cells: effect of stimulation with phytohaemagglutinin.
PMID:12631248
Tyrosine hydroxylase isoenzyme I is present in human melanosomes: a possible novel function in pigmentation.
PMID:15287903
Effects of phosphorylation by protein kinase A on binding of catecholamines to the human tyrosine hydroxylase isoforms.
PMID:16338639
The assays of activities and function of TH, AADC, and GCH1 and their potential use in ex vivo gene therapy of PD.
PMID:1680128
Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing.
PMID:17135716
Co-expression of tyrosine hydroxylase and GTP cyclohydrolase I in arginine vasopressin-synthesizing neurons of the human supraoptic nucleus demonstrated by laser microdissection and real-time PCR.
PMID:17391063
Characterisation of novel splicing variants of the tyrosine hydroxylase C-terminal domain in human neuroblastic tumours.
PMID:17520326
Oxygen dependence of tyrosine hydroxylase.
PMID:18343820
Glial cell line-derived neurotrophic factor reverses ethanol-mediated increases in tyrosine hydroxylase immunoreactivity via altering the activity of heat shock protein 90.
PMID:19703902
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1.
PMID:21392500
Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme.
PMID:24753243
Functional studies of tyrosine hydroxylase missense variants reveal distinct patterns of molecular defects in Dopa-responsive dystonia.
PMID:2896667
Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector.
PMID:34922205
Tyrosine hydroxylase activity is regulated through the modification of the 176th cysteine residue.
PMID:7715703
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development.
PMID:8528210
Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene.
Reactome:R-HSA-209823
Tyrosine is hydroxylated to dopa