Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Mutations in the skeletal muscle alpha-actin gene in patients with actin myopathy and nemaline myopathy.
Nemaline myopathy caused by mutations in the muscle alpha-skeletal-actin gene.
Production of human skeletal alpha-actin proteins by the baculovirus expression system.
Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation.
Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms.
Interaction of the mycobacterial heparin-binding hemagglutinin with actin, as evidenced by single-molecule force spectroscopy.
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Protein profile of exosomes from trabecular meshwork cells.
Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.
Architecture of the human interactome defines protein communities and disease networks.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Antisense oligodeoxynucleotide complementary to smooth muscle alpha-actin inhibits endothelial-mesenchymal transformation during chick cardiogenesis.
Defining alpha-skeletal and alpha-cardiac actin expression in human heart and skeletal muscle explains the absence of cardiac involvement in ACTA1 nemaline myopathy.
Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation.
Myotilin is mutated in limb girdle muscular dystrophy 1A.
The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.
Structural differences explain diverse functions of Plasmodium actins.
A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.
SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.
Release Of ADP From Myosin
DGC complex binds AGRN and HSPG2
CDH1-associated CTNNA1 binds VCL
CDH1 forms homotypic trans-dimers
CDH1-associated CTNNA1 binds F-actin
Affinage mechanistic annotation for ACTA1 (human)
ACTA1 bioinformatics: WITH/FROM provenance and actin-isoform peptide specificity
UniProtKB entry P68133 (ACTS_HUMAN)