MYC3 (At5g46760; UniProt Q9FIP9) curation notes

2026-10-06 — initial review (jasmonate_coi1_jaz_signaling module)

• Fetched with just fetch-gene ARATH MYC3; UniProt record checked: MYC3_ARATH, Q9FIP9, At5g46760 (bHLH005, ATR2).
• just deep-research-falcon ARATH MYC3 failed (HTTP 402); review based on cached publications.

Key evidence

• JAZ target, nuclear, G-box binding like MYC2, acts additively with MYC2 PMID:21335373.
• Nearly identical DNA specificity to MYC2 PMID:21335373.
• Transactivates JAZ promoters PMID:21321051.
• Structure: JAZ9 Jas helix binds MYC3 N-terminus and blocks MED25 PMID:26258305.
• Represses FT in photoperiodic flowering [PMID:31178399, abstract only].

Decisions

• Protein binding rows resolved by partner (supporting_entities): JAZ partners -> MODIFY to GO:0001222 transcription corepressor binding; MED25 -> MODIFY to GO:0001223 transcription coactivator binding; FT-paper row (AT1G65480) -> REMOVE (uninformative; repo policy disallows MARK_AS_OVER_ANNOTATED for protein binding).
• response to jasmonic acid -> MODIFY to GO:0009867 for consistency with MYC2 review.