Gene Ontology annotation reference GO_REF:0000002
Gene Ontology annotation reference GO_REF:0000024
Gene Ontology annotation reference GO_REF:0000033
CG18547 PANTHER tree placement and AKR catalytic tetrad analysis
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CG18547 is one of three Drosophila paralogs under a lineage duplication, co-orthologous to C. elegans mec-14 at the Ecdysozoa node; yeast ARA2 and plant LGALDH sit in separate fungal and plant clades.
"LCA with C. elegans mec-14 (Q20127) is PTN000199440 (Ecdysozoa, speciation)"
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The AKR catalytic tetrad is retained.
"CG18547 retains the complete Asp-Tyr-Lys-His tetrad"
CG18547 deep research report (falcon)
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The CG18547 transcript marks a GST-rich lymph gland hemocyte subcluster; no biochemical study of the protein exists.
"CG18547 appeared in the marker analysis and, together with CG3397, was identified as a specific marker of a **GST-rich** cluster"