Annotation inferences using phylogenetic trees
GeneChip expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes.
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PvdS-dependent iron-regulated genes include novel pyoverdine biosynthetic genes.
"Under low-iron conditions, expression of 26 genes or operons was reduced in a DeltapvdS mutant compared with wild type, including numerous novel pyoverdine biosynthetic genes."
Identification and characterization of novel pyoverdine synthesis genes in Pseudomonas aeruginosa.
The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa.
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PA2412 is needed for normal pyoverdine production but not for ferripyoverdine uptake.
"Our results demonstrate that PA2412 is necessary for the production or secretion of pyoverdine at normal levels. The PA2412 deletion strain is able to use exogenously produced pyoverdine, showing that there is no defect in the uptake or utilization of the iron-pyoverdine complex."
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PA2412 is co-expressed with the pyoverdine synthetases.
"Coexpressed with the pyoverdine synthetic enzymes is a 72-amino acid MbtH-like family member designated PA2412."