GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms.
GO_REF:0000003
Gene Ontology annotation based on Enzyme Commission mapping
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods.
PMID:11007892
The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress.
PMID:11519011
Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis.
PMID:12457401
Desmosterolosis presenting with multiple congenital anomalies and profound developmental delay.
PMID:15577914
Regulation of cellular response to oncogenic and oxidative stress by Seladin-1.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:25637936
The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally.
PMID:30021884
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Reactome:R-HSA-191273
Cholesterol biosynthesis
Reactome:R-HSA-196417
Reduction of desmosterol to cholesterol
Reactome:R-HSA-6807047
Cholesterol biosynthesis via desmosterol
Reactome:R-HSA-6807062
Cholesterol biosynthesis via lathosterol
Reactome:R-HSA-6807064
DHCR24 reduces ZYMOL to ZYMSTNL
Reactome:R-HSA-9755937
DHCR24 reduces LAN to 24,25-dhLAN