ERECTA (At2g26330, Q42371) curation notes

Session 2026-10-06 (stomatal_lineage_development module). Folder named ERECTA (UniProt primary name ERECTA; synonym ER). Initial just fetch-gene ARATH ERECTA was replaced by an accession-based fetch (Q42371 --alias ERECTA). Falcon deep research failed (HTTP 402).

Key findings

• LRR-RLK: cytoplasmic kinase, TM, extracellular LRRs PMID:8624444.
• Primary receptor for EPF2; direct, saturable binding PMID:22241782; ER-family triple mutants have clustered stomata PMID:16002616.
• EPF ligands induce ER-SERK heteromerization; mutual transphosphorylation; SERKs act upstream of the MAPK cascade PMID:26320950.
• Plasma membrane localization of functional ERECTA-YFP PMID:26203655.
• Inflorescence architecture via YDA-MKK4/5-MPK3/6 PMID:23263767.
• Pleiotropic secondary roles: transpiration efficiency PMID:16007076, thermotolerance PMID:26280413, vascular patterning with PXY PMID:23578929, ovule MMC fate PMID:37606225, resistance to Ralstonia PMID:14617092 and Plectosphaerella [PMID:15998304; PMID:19589071].

Curation decisions

• Core MF: transmembrane receptor protein serine/threonine kinase activity GO:0004675 (NEW; existing ISS GO:0019199 accepted as parent).
• Core BPs: negative regulation of stomatal complex development (GO:2000122, NEW; stomatal complex morphogenesis rows MODIFIED to it) and inflorescence morphogenesis (GO:0048281, accepted).
• 13 high-throughput ectodomain-network protein binding rows (PMID:29320478) REMOVED as uninformative; stomagen protein binding MODIFIED to peptide binding.
• Mitochondrion HDA (PMID:14671022) MARK_AS_OVER_ANNOTATED (likely membrane contamination; ERECTA-YFP at plasma membrane).
• Lease et al. 2001 New Phytologist IDA (DOI:10.1046/j.1469-8137.2001.00150.x) title verified via Crossref; not cached; accepted.
• No GO-CAM models contain ERECTA.