Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin.
Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism.
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2.
Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci.
The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions.
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.
CTCF physically links cohesin to chromatin.
The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome.
Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster.
Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting.
Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus.
Vigilin interacts with CCCTC-binding factor (CTCF) and is involved in CTCF-dependent regulation of the imprinted genes Igf2 and H19.
JARID1B is a luminal lineage-driving oncogene in breast cancer.
A proteome-scale map of the human interactome network.
CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites.
CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.
CGGBP1 regulates CTCF occupancy at repeats.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.
The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation.
A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers.
Jpx RNA activates Xist by evicting CTCF.
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function.
CTCF Binding Polarity Determines Chromatin Looping.
Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops.
CTCF maintains centromere function and mitotic fidelity.
CTCF curated evidence and source-access summary