Zw10 (Zeste-white 10; Q9W4X9) notes

Identity

ZW10 family (PANTHER PTHR12205); subunit of the Rod-Zw10-Zwilch (RZZ) kinetochore complex and, with Rint1, of the ER/Golgi NRZ (Dsl1-like) tethering machinery.

Rod and Zw10 are required for the metaphase (spindle assembly) checkpoint PMID:11146659.
Zw10 and Rod are interdependent and form a large soluble complex [PMID:11590237 "require each other for their recruitment to the mitotic apparatus"; "constituents of a large (700-900 kDa), soluble macromolecular complex"].
Zwilch identified as third subunit; RZZ recruits dynein PMID:12686595.
RZZ is required for Mad2 kinetochore recruitment PMID:15886105.
Spindly links RZZ to dynein PMID:17576797.
Membrane-trafficking role in spermatocytes [PMID:22685323 "Zw10 is enriched at both the Golgi stacks and the ER of Drosophila spermatocytes"; "Loss of either Zw10 or Rint1 results in frequent failures of spermatocyte cytokinesis"; "furrow ingression halts prematurely due to defective plasma membrane addition"].
Rab18 affinity chromatography retrieves Zw10 and Rod PMID:25453831.

Two core roles: RZZ kinetochore adaptor (SAC, dynein/Mad1-Mad2 recruitment) and NRZ ER-Golgi trafficking (Golgi organization; membrane supply in cytokinesis).
IBA "ER to Golgi vesicle-mediated transport" (anterograde) modified to the direction-neutral "Golgi vesicle transport" (GO:0048193): the Dsl1/NRZ complex tethers vesicles returning from the Golgi (retrograde), and the fly data show an ER-Golgi trafficking role without supporting the anterograde direction.
Generic centromeric-region location kept as non-core (kinetochore is the core location).
Deep research (falcon) failed twice (OOM/timeout, perplexity fallback unavailable) but the falcon job later completed (Zw10-deep-research-falcon.md); it agrees Zw10 is a nonenzymatic RZZ scaffold with a separable membrane role ["this membrane-associated activity is distinguishable experimentally from its canonical kinetochore role"] and cautions that fly Zw10 is not shown to tether COPI vesicles directly.