Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
A novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAc.
Mutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of α-dystroglycan.
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Patient material and zebrafish perturbations support B3GALNT2 involvement in functional alpha-dystroglycan glycosylation; these are cellular and organismal endpoints, not purified-enzyme measurements.
"Together these results demonstrate a role
for B3GALNT2 in the glycosylation of α-DG"
SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function.
Identification of mammalian glycoproteins with type-I LacdiNAc structures synthesized by the glycosyltransferase B3GALNT2.
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Cultured-cell experiments support B3GALNT2-dependent modification of intracellular glycoprotein N-glycans; the endogenous substrate repertoire and physiological effects remain incompletely resolved.
"B3GALNT2 primarily transferred LDN to intracellular glycoproteins"
A reference map of the human binary protein interactome.
B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1
DAG1 core M3 glycosylations
UniProtKB reviewed record for B3GALNT2 (Q8NCR0)