Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

PMID:9466253

The secretion apparatus of Pseudomonas aeruginosa: identification of a fifth pseudopilin, XcpX (GspK family).

XcpX is a bitopic inner-membrane pseudopilin processed by PilD/XcpA; its conserved glycine is required for function.

PMID:9818381

GSP-dependent protein secretion in gram-negative bacteria: the Xcp system of Pseudomonas aeruginosa.

Review of the Xcp type II secretion machinery of P. aeruginosa.

PMID:16012171

XcpX controls biogenesis of the Pseudomonas aeruginosa XcpT-containing pseudopilus.

XcpX controls pseudopilus length and interacts directly with XcpT.

"Our results indicate that XcpT and XcpX directly interact with each other"

PMID:19828448

The XcpV/GspI pseudopilin has a central role in the assembly of a quaternary complex within the T2SS pseudopilus.

XcpX forms the XcpU-V-W-X tip complex with the other minor pseudopilins.

PMID:30346996

Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.

Crystal structure of XcpVWX; XcpX sits at the top of the tip complex and binds calcium (ITC). A transposon xcpX mutant still secreted protease.

"The calcium binding of XcpX was also confirmed by isothermal titration calorimetry"

file:PSEAE/xcpX/xcpX-uniprot.txt

UniProt entry Q00518 (GSPK_PSEAE)