Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Combined Automated Annotation using Multiple IEA Methods

Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger.

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.

The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretion.

NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state.

Identification of residues that control Li(+) versus Na(+) dependent Ca(2+) exchange at the transport site of the mitochondrial NCLX.

Mitochondria control store-operated Ca(2+) entry through Na(+) and redox signals.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

Sodium/Calcium exchangers

K+-independent Li+/Ca2+ exchanger transport

Mitochondrial calcium ion transport

SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)

Structure and mechanism of the mitochondrial calcium transporter NCLX.

Molecular mechanisms of mitochondrial Ca(2+) exchanger NCLX.

TMEM65 regulates and is required for NCLX-dependent mitochondrial calcium efflux.

TMEM65 functions as the mitochondrial Na(+)/Ca(2+) exchanger.

Mitochondrial sodium-calcium exchange-Can TMEM65 do it alone?