GO_REF:0000033

Annotation inferences using phylogenetic trees

GO_REF:0000107

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:human/MYL10/MYL10-uniprot.txt

UniProtKB Q9BUA6: human MYL10 sequence and curated features

file:HORSE/MYL10/MYL10-uniprot.txt

UniProtKB A0A9L0TJE1: horse MYL10 sequence and domain features

file:HORSE/MYL10/MYL10-bioinformatics/RESULTS.md

MYL10 human-horse sequence comparison

The selected horse MYL10 sequence conserves the first human EF-hand calcium-binding positions.

"| BINDING | 97–97 | 83 | 1/1 |"

file:HORSE/MYL10/MYL10-bioinformatics/RESULTS-rereview.md

MYL10 (horse A0A9L0TJE1): re-review family placement and gene-model comparison

The A0A9L0TJE1 light-chain core is 98.7% identical to mouse MYL10 and 83.6% identical to human MYL2, the closest paralog.

"| Q62082 | MYL10_MOUSE | 202 | 150/152 | 0.987 | 0 |"
Human MYL10 carries a 34-residue insertion before the first EF-hand that is absent from mouse, rat and horse MYL10.

"mouse, rat and horse MYL10 join these two segments directly."
The four horse MYL10 UniProt entries share one core and differ in their N-terminal segment (and, for F6XM32, its C-terminus).

"| F6XM32 | 171 | 16 | `MAPRRARKRAEGAAS` | False |"

PMID:1628631

A novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible.

The mouse MYL10 ortholog (PLRLC) is expressed in precursor lymphocytes and is induced by IL-7.

"suggest an important role for PLRLC during lymphocyte development"

PMID:33657370

Optic nerve regeneration screen identifies multiple genes restricting adult neural repair.

Mouse Myl10 editing in retinal ganglion cells enhanced axon regeneration after optic nerve crush; the mechanism was not investigated.

"Literature regarding the function of Myl10 is scarce"