Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic Gene Ontology annotation based on Rhea mapping

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase.

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.

A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.

Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.

DELE1 oligomerization promotes integrated stress response activation.

The HRI branch of the integrated stress response selectively triggers mitophagy.

DELE1(143-515) binds EIF2AK1 (HRI)

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies.

Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias.

Identification of crucial histidines for heme binding in the N-terminal domain of the heme-regulated eIF2alpha kinase.

A mitochondrial iron-responsive pathway regulated by DELE1.