GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000113
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10608869
The human and mouse GATA-6 genes utilize two promoters and two initiation codons.
PMID:11889139
Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription.
PMID:12615657
GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells.
PMID:14988427
GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1.
PMID:15016828
Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling.
PMID:16177791
DNA sequence and analysis of human chromosome 18.
PMID:16199874
Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts.
PMID:16968778
A conserved role for a GATA transcription factor in regulating epithelial innate immune responses.
PMID:17626241
GATA-6 mediates human bladder smooth muscle differentiation: involvement of a novel enhancer element in regulating alpha-smooth muscle actin gene expression.
PMID:17785913
Transcription factor GATA-6 in the human adrenocortex: association with adrenal development and aging.
PMID:17848411
Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester.
PMID:18177748
GATA-6 is a novel transcriptional repressor of the human Tenascin-C gene expression in fibroblasts.
PMID:18669648
A quantitative atlas of mitotic phosphorylation.
PMID:18671946
Statins activate GATA-6 and induce differentiated vascular smooth muscle cells.
PMID:19413330
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PMID:19497978
The mediator complex subunit 1 enhances transcription of genes needed for adrenal androgen production.
PMID:19666519
GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling.
PMID:20068231
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PMID:20206639
The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression.
PMID:20581743
Identification of GATA6 sequence variants in patients with congenital heart defects.
PMID:20631719
A novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect.
PMID:20864106
PTEN differentially regulates expressions of ICAM-1 and VCAM-1 through PI3K/Akt/GSK-3β/GATA-6 signaling pathways in TNF-α-activated human endothelial cells.
PMID:21127043
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling.
PMID:21828274
HEB and E2A function as SMAD/FOXH1 cofactors.
PMID:22158542
GATA6 haploinsufficiency causes pancreatic agenesis in humans.
PMID:22750565
GATA6 loss-of-function mutation in atrial fibrillation.
PMID:22824924
Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation.
PMID:25068583
miR-10a regulates proliferation of human cardiomyocyte progenitor cells by targeting GATA6.
PMID:26786210
The formation and function of the cardiac conduction system.
PMID:27756709
Gain-of-function mutations in GATA6 lead to atrial fibrillation.
PMID:28112733
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PMID:28473536
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
PMID:33082341
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis.
PMID:33443158
GATA6 is a regulator of sinus node development and heart rhythm.
PMID:8975704
The human GATA-6 gene: structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals.
PMID:9294001
Molecular cloning of human GATA-6 DNA binding protein: high levels of expression in heart and gut.
PMID:9315713
GATA-6 DNA binding protein expressed in human gastric adenocarcinoma MKN45 cells.
PMID:9566909
Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation.
PMID:9593712
GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest.
Reactome:R-HSA-5683888
LMCD1 binds GATA6, sequestering it
Reactome:R-HSA-5685296
GATA6 binds SFTPA genes
Reactome:R-HSA-9823952
EOMES, SMAD2,3, and GATA6 bind the CXCR4 gene
Reactome:R-HSA-9823977
Expression of GATA6 in definitive endoderm
Reactome:R-HSA-996755
ZFPM proteins bind GATA proteins
UniProt:Q92908
UniProtKB entry Q92908 (GATA6_HUMAN)