Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods.

Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome). An intermediate clinical phenotype caused by substitution of valine for glycine at position 137 of arylsulfatase B.

Distinct effects of N-acetylgalactosamine-4-sulfatase and galactose-6-sulfatase expression on chondroitin sulfates.

Arylsulfatase B regulates colonic epithelial cell migration by effects on MMP9 expression and RhoA activation.

Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

ARSB hydrolyses DS

SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases

ARSB hydrolyses C4S/C6S chains

Defective ARSB does not hydrolyse C4S/C6S chains

Exocytosis of azurophil granule lumen proteins

Exocytosis of ficolin-rich granule lumen proteins

Defective ARSB does not hydrolyse DS

UniProt entry for ARSB (P15848)

Autophagy-related changes of arylsulphatases A and B in rat liver lysosomes.

Enzymic changes in the cervix of the rat and hamster during the oestrous cycle and the effect of steroids.

The effect of pH on the kinetics of arylsulphatases A and B.

Characterization of liver lysosomal enzyme activity in hepatocytes, Kupffer and endothelial cells during aging: effect of dietary restriction.

Inability of thiol compounds to restore CNS arylsulfatases inhibited by methyl mercury.

Arylsulfatase B modulates neurite outgrowth via astrocyte chondroitin-4-sulfate: dysregulation by ethanol.

ARSB source assessment and functional synthesis

Structure of a human lysosomal sulfatase.