Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Ribosome. The structure of the human mitochondrial ribosome.
Structure and Function of the Mitochondrial Ribosome.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP
MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA
55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed
Hydrolysis of GTP and dissociation of 28S and 39S subunits
GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA
MRRF binds 55S ribosome:mRNA:tRNA
55S ribosome:MTRF1 hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed
Stalled 55S mitochondrial ribosome is dissociated to yield 28S subunit and 39S subunit:mRNA:peptidyl-tRNA:tRNA
MTRF1 and GTP bind 55S ribosome:MT-CO1,MT-ND6 mRNA:peptidyl-tRNA at P-site:tRNA at E-site
ICT1 hydrolyzes the peptidyl-tRNA bond of the nascent polypeptide
55S mitochondrial ribosome:non-stop mRNA binds ICT1 (MRPL58)
Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia.