Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.
CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations.
Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1.
CCM1 regulates vascular-lumen organization by inducing endothelial polarity.
Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling.
KRIT1 regulates the homeostasis of intracellular reactive oxygen species.
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation.
Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations.
Phospho-tyrosine dependent protein-protein interaction network.
Widespread macromolecular interaction perturbations in human genetic disorders.
Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.
Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22.
UniProtKB O00522: human KRIT1 sequence and curated functions
A mechanism of Rap1-induced stabilization of endothelial cell--cell junctions.