Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Combined Automated Annotation using Multiple IEA Methods
Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.
Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography.
-
Most yeast mitoribosomes reside next to the inner membrane; membrane contacts are made by 21S rRNA ES 96-ES1 and Mba1 (large subunit side).
"Most mitoribosomes reside in immediate proximity to the inner mitochondrial membrane"
The structure of the yeast mitochondrial ribosome.
-
Cryo-EM structure of the yeast mitoribosome; Sws2 (P53937) modelled as uS13m (chain MM) in the mt-SSU, contributing to mitochondria-specific intersubunit bridges mB8, mB9, mB10 and mB13 (supplementary tables).
"The mitoribosomal small subunit has been built de novo and includes 15S ribosomal RNA (rRNA) and 34 proteins"
Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions.
Uncovering novel cell cycle players through the inactivation of securin in budding yeast.
-
SWS2 was named for its synthetic sickness with pds1 (securin) deletion in an SGA screen; the basis of the interaction is unknown.
"SWS2 and QRI5 encode mitochondria-associated proteins of unknown function"
-
The authors report (data not shown) that sws2 deletion cells accumulate early in the cell cycle.
"flow cytomerty analysis suggested that sws2 Δ and qri5 Δ strains accumulate early in the cell cycle (data not shown)"
Systematic analysis of nuclear gene function in respiratory growth and expression of the mitochondrial genome in S. cerevisiae.
-
SWS2 is among 254 high-confidence pet genes, listed under mitochondrial translation and RNA maturation.
"254 high confidence pet genes in yeast, 79% of which encode mitochondrial proteins"
-
sws2 deletion mutants lose mtDNA ([rho0]), listed in the table of genes required for maintenance of mtDNA.
"MSK1YNL073WSWS2YNL081C"
Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames.
-
ynl081c deletion grows with reduced rate; Ynl081c-GFP gives dot-shaped and elongated structures, which UniProt cites as mitochondrial localization.
"three deletion strains (ynl080c, ynl081c and ynl225c) grew with reduced rates"
The yeast peroxisomal proteome at absolute quantitative scale.
UniProt entry P53937 (SWS2_YEAST)
Supplementary materials of PMID:28154081 (yeast mitoribosome structure)
A novel single-cell screening platform reveals proteome plasticity during yeast stress responses.
SGD gene description for SWS2 (yeast)