Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repair.

Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome.

Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG.

Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen.

Suppression of UV-induced apoptosis by the human DNA repair protein XPG.

Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome.

UV-induced apoptosis in XPG-deficient fibroblasts involves activation of CD95 and caspases but not p53.

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability.

Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.

The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.

Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.

XPG protein has a structure-specific endonuclease activity.

Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies.

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair.

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair.

Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein.

Ultraviolet-induced movement of the human DNA repair protein, Xeroderma pigmentosum type G, in the nucleus.

The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21.

Nucleotide excision repair 3' endonuclease XPG stimulates the activity of base excision repairenzyme thymine glycol DNA glycosylase.

Formation of the pre-incision complex in GG-NER

DNA polymerases delta, epsilon or kappa bind the GG-NER site

3'-incision of DNA by ERCC5 (XPG) in GG-NER

5'- incision of DNA by ERCC1:ERCC4 in GG-NER

Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER

Transcription-Coupled Nucleotide Excision Repair (TC-NER)

ERCC5 and RPA bind TC-NER site

Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER

5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER

DNA polymerases delta, epsilon or kappa bind the TC-NER site

3' incision by ERCC5 (XPG) in TC-NER

Structural basis of TFIIH activation for nucleotide excision repair.

Human xeroderma pigmentosum group G gene encodes a DNA endonuclease.

Transcription factor TFIIH and DNA endonuclease Rad2 constitute yeast nucleotide excision repair factor 3: implications for nucleotide excision repair and Cockayne syndrome.

Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease.