Identification of the putrescine biosynthetic genes in Pseudomonas aeruginosa and characterization of agmatine deiminase and N-carbamoylputrescine amidohydrolase of the arginine decarboxylase pathway.
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speC encodes ODC; ODC and ADC activities are similar and either suffices for growth.
"The activities of the two decarboxylases were similar and each enzyme alone appeared to direct sufficient formation of the polyamine for normal growth."
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A speA speC double mutant is a putrescine auxotroph.
"A mutant defective in both speA and speC was a putrescine auxotroph."
speC review notes
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Live QuickGO query shows human AZIN1 inherits ODC activity from PTN000159726 while AZIN2 carries a NOT.
"AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes"
Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
UniProtKB entry Q9HVQ3 for Pseudomonas aeruginosa PAO1 SpeC