Siderophore-mediated cell signalling in Pseudomonas aeruginosa: divergent pathways regulate virulence factor production and siderophore receptor synthesis.
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FpvR negatively regulates FpvI, and controls PvdS-dependent production of pyoverdine and other virulence factors.
"FpvR negatively regulates the activity of a second ECF sigma factor, FpvI, which is required for the synthesis of FpvA"
Interactions between an anti-sigma protein and two sigma factors that regulate the pyoverdine signaling pathway in Pseudomonas aeruginosa.
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The cytoplasmic region of FpvR binds and inhibits FpvI and PvdS.
"The cytoplasmic region of FpvR bound to and inhibited both FpvI and PvdS when the proteins were co-expressed in Escherichia coli."
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FpvR spans the cytoplasmic membrane.
"In the absence of pyoverdine the anti-sigma factor FpvR that spans the cytoplasmic membrane inhibits the activities of both FpvI and PvdS"
Automatic assignment of GO terms using logical inference, based on on inter-ontology links