Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway.
Subunit composition of the human cytoplasmic dynein-2 complex.
A proteome-scale map of the human interactome network.
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking.
Emerging mechanisms of dynein transport in the cytoplasm versus the cilium.
Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking.
Structure of the dynein-2 complex and its assembly with intraflagellar transport trains.
Cytoplasmic dynein-2 at a glance.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.
Multimodal cell maps as a foundation for structural and functional genomics.
Assembly of the anterograde IFT train
Assembly of the retrograde IFT train
The anterograde IFT train dissociates
The retrograde IFT train dissociates
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
Falcon deep research report for DYNC2I2 (human)
Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy.
Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.
DYNC2I2 raw-data evidence audit
UniProtKB Q96EX3 (DYNC2I2)
Subcellular - DYNC2I2 - The Human Protein Atlas