A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol.
alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids.
GABA(A) receptors can initiate the formation of functional inhibitory GABAergic synapses.
Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.
Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology.
Inhibitory synapse formation in a co-culture model incorporating GABAergic medium spiny neurons and HEK293 cells stably expressing GABAA receptors.
Structure of a human synaptic GABA(A) receptor.
Structural basis of neurosteroid anesthetic action on GABA(A) receptors.
Cryo-EM structure of the human α1β3γ2 GABA(A) receptor in a lipid bilayer.
Mechanisms of inhibition and activation of extrasynaptic αβ GABA(A) receptors.
Resolving native GABA(A) receptor structures from the human brain.
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
A mutation in the GABA(A) receptor alpha(1)-subunit is associated with absence epilepsy.
Novel α1 and γ2 GABAA receptor subunit mutations in families with idiopathic generalized epilepsy.
GABRA1 and STXBP1: novel genetic causes of Dravet syndrome.
Diagnostic Targeted Resequencing in 349 Patients with Drug-Resistant Pediatric Epilepsies Identifies Causative Mutations in 30 Different Genes.
Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor.
An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA(A) Receptors.
Impairment of Inhibitory Synapse Formation and Motor Behavior in Mice Lacking the NL2 Binding Partner LHFPL4/GARLH4.
Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens)
The kinesin KIF21B participates in the cell surface delivery of γ2 subunit-containing GABAA receptors.