GUT1 (YHL032C, UniProt P32190) notes

Activity / role

• Glycerol kinase PMID:8358828; PMID:8358828
• Required for glycerol utilisation only PMID:8358828
• Reaction glycerol + ATP -> sn-G3P + ADP, EC 2.7.1.30 [UniProt:P32190]

Localization

• Cytoplasm (Huh 2003 GFP, PMID:14562095); mitochondrial import in vitro PMID:17054397 -> kept non-core.

Curation observations

• IBA triglyceride metabolic process (mammalian GK lipid physiology) -> over-annotated.
• Generic kinase/phosphotransferase IEA -> MODIFY to glycerol kinase.
• protein binding (Gpp2p) removed.