erg6 (SPBC16E9.05; UniProt O14321) notes

• Fetched accession verified O14321 (ERG6_SCHPO). Sterol 24-C-methyltransferase, Erg6/SMT family [UniProt:O14321 "Erg6/SMT family"].
• Reaction: [UniProt:O14321 "Reaction=zymosterol + S-adenosyl-L-methionine = fecosterol + S-"]; UniProt also lists lanosterol -> eburicol [UniProt:O14321 "Reaction=lanosterol + S-adenosyl-L-methionine = eburicol + S-adenosyl-"] based on PMID:8586261 (inference from sterol profiles, not an enzyme assay). GO has no lanosterol 24-C-methyltransferase term; GO:0003838 is defined on zymosterol.
• Deletion: PMID:18310029; PMID:23145048; erg6 deletion strongly raises lanosterol PMID:23145048 - consistent with the lanosterol-methylation branch being blocked.
• Localisation: ORFeome called nucleus (UniProt: "Nucleus {ECO:0000269|PubMed:16823372}"), ER only inferred. Kept nucleus as non-core (cannot check images; possibly nuclear envelope/ER). Budding-yeast Erg6 is ER + lipid droplet.
• Induction by Sre1 under anaerobiosis PMID:16537923.
• Budding-yeast ERG6 review: core GO:0003838, LD + ER. S. pombe core location set to ER only (no LD evidence in fission yeast).
• GO-CAM 66c7d41500002088: erg6 GO:0003838 in ER, -> erg2. Agrees.