Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

Combined Automated Annotation using Multiple IEA Methods

VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells.

Brca1 and Brca2 protein expression patterns in different tissues of murine origin.

Genomic instability in mice lacking histone H2AX.

BRCA1 supports XIST RNA concentration on the inactive X chromosome.

Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia.

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway.

Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.

BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function.

DNA damage-induced BARD1 phosphorylation is critical for the inhibition of messenger RNA processing by BRCA1/BARD1 complex.

p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.

Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex.

BRCA1 affects global DNA methylation through regulation of DNMT1.

BRCA1 is an essential regulator of heart function and survival following myocardial infarction.

BRCA1 tumor suppressor network: focusing on its tail.

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.

HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.

FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice.

The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.

CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.

GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.

Formation of Meiotic Single-stranded Invasion Complex

Atr Phosphorylates Histone H2A.X at Unsynapsed Regions

Formation of Meiotic Heteroduplex

Recruitment of Atr Kinase to Unsynapsed Regions

Recruitment of Brca1 to Unsynapsed Regions

UniProtKB record for mouse Brca1 (P48754)

Falcon deep research synthesis for mouse Brca1