Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha.
Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis.
Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2.
GADD34 induces p53 phosphorylation and p21/WAF1 transcription.
Functional proteomics mapping of a human signaling pathway.
Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein.
Toward an understanding of the protein interaction network of the human liver.
The unfolded protein response: integrating stress signals through the stress sensor IRE1α.
The endoplasmic reticulum stress response in aging and age-related diseases.
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling.
Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.
Substrate recognition determinants of human eIF2α phosphatases.
STING-NF-κB signaling builds an influenza spillover barrier.
Mammalian GADD34, an apoptosis- and DNA damage-inducible gene.
PP1CC dephosphorylates TGFBR1
Smad7 recruits GADD34:PP1CC to phosphorylated TGF-beta receptor complex