Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Subtilase SprP exerts pleiotropic effects in Pseudomonas aeruginosa.
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Catalytic Ser499 is required for protease activity.
"SprP variant S499A which had the catalytic serine replaced by alanine also did not show protease activity"
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Deletion of sprP abolishes all three motility types and increases biofilm formation.
"Examination of P. aeruginosa ΔsprP for its swimming, swarming, and twitching motility revealed that all three types of motility were virtually abolished"
Functional expression, purification, and biochemical properties of subtilase SprP from Pseudomonas aeruginosa.
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Purified SprP is a serine protease hydrolysing casein, inhibited by AEBSF and TPCK.
"Our results confirm the classification of SprP as a serine protease"
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SprP is autocatalytically activated.
"SprP is autocatalytically activated by proteolysis"
UniProt entry Q9I496 (Q9I496_PSEAE)