GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000113
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
PMID:10037502
Complete sequence of a novel protein containing a femtomolar-activity-dependent neuroprotective peptide.
PMID:11438390
Vasoactive intestinal peptide and related molecules induce nitrite accumulation in the extracellular milieu of rat cerebral cortical cultures.
PMID:12212775
NAP accelerates the performance of normal rats in the water maze.
PMID:14706557
The neuroprotective peptide NAP inhibits the aggregation of the beta-amyloid peptide.
PMID:15314252
NAP mechanisms of neuroprotection.
PMID:15800376
Activity-dependent neurotrophic factor-9 and NAP promote neurite outgrowth in rat hippocampal and cortical cultures.
PMID:15963648
Synergistic effects of the peptide fragment D-NAPVSIPQ on ethanol inhibition of synaptic plasticity and NMDA receptors in rat hippocampus.
PMID:16023261
Neuropeptide receptor transcripts are expressed in the rat clitoris and oscillate during the estrus cycle in the rat vagina.
PMID:16845437
Subcellular localization and secretion of activity-dependent neuroprotective protein in astrocytes.
PMID:16893427
Peptide neuroprotection through specific interaction with brain tubulin.
PMID:16938277
Neuroprotective effect of the peptides ADNF-9 and NAP on hypoxic-ischemic brain injury in neonatal rats.
PMID:17222401
Activity-dependent neuroprotective protein (ADNP) differentially interacts with chromatin to regulate genes essential for embryogenesis.
PMID:18072088
Expression of activity-dependent neuroprotective protein in the brain of adult rats.
PMID:19047645
Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling.
PMID:19130308
Nitric oxide regulates activity-dependent neuroprotective protein (ADNP) in the dentate gyrus of the rodent model of kainic acid-induced seizure.
PMID:20562864
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.
PMID:21888893
Analysis of the human HP1 interactome reveals novel binding partners.
PMID:24531329
A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP.
PMID:24981860
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
PMID:25178163
The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins.
PMID:27705803
A High-Density Map for Navigating the Human Polycomb Complexome.
PMID:27903678
ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.
PMID:29795351
Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.
PMID:31491387
The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.
PMID:32533114
ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:36631597
The cytoplasmic localization of ADNP through 14-3-3 promotes sex-dependent neuronal morphogenesis, cortical connectivity, and calcium signaling.
PMID:36950384
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
PMID:38960717
ChAHP2 and ChAHP control diverse retrotransposons by complementary activities.
PMID:41174994
ADNP Exhibits Methyltransferase Activity in Overexpression Systems and Modulates DNA and Histone Methylation.
PMID:42413491
Remodeling activity of ChAHP restricts transcription factor access to chromatin.
PMID:42413492
ChAHP silences SINE retrotransposons by inhibiting TFIIIB recruitment.
Reactome:R-HSA-9940477
Formation of ChAHP complex
file:human/ADNP/ADNP-bioinformatics/RESULTS.md
Ensembl Compara donor provenance for human ADNP (Q9H2P0)
file:human/ADNP/ADNP-deep-research-affinage.md
Affinage mechanistic annotation for ADNP (human)
PMID:21267468
HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats.
PMID:40498903
POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor population.