Curator notes for mouse Edn1 review

Falcon deep research report for mouse Edn1

UniProtKB record for mouse Edn1

QuickGO export for mouse Edn1

Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

Combined Automated Annotation using Multiple IEA Methods

Endothelin in the central control of cardiovascular and respiratory functions.

Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis.

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport.

The first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13.

Endothelin-1 regulates the dorsoventral branchial arch patterning in mice.

Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.

Temporal requirement of signaling cascade involving endothelin-1/endothelin receptor type A in branchial arch development.

Collecting duct-specific knockout of endothelin-1 alters vasopressin regulation of urine osmolality.

Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention.

Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons.

Paracrine regulation of the resumption of oocyte meiosis by endothelin-1.

NFATc3 contributes to intermittent hypoxia-induced arterial remodeling in mice.

Low blood pressure in endothelial cell-specific endothelin 1 knockout mice.

Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation.

Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries.

Endothelin-1 inhibits sodium reabsorption by ET(A) and ET(B) receptors in the mouse cortical collecting duct.

Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms.

Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis.

Venous endothelin guides sympathetic innervation of the developing mouse heart.

Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling.

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts.

Postotic and preotic cranial neural crest cells differently contribute to thyroid development.

Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx.

Glomerular Endothelial Mitochondrial Dysfunction Is Essential and Characteristic of Diabetic Kidney Disease Susceptibility.

Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin.

ET(A)R and protein kinase A pathway mediate ET-1 sensitization of TRPA1 channel: A molecular mechanism of ET-1-induced mechanical hyperalgesia.

Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract.

Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells.

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.

Effects of endothelin-1 on isolated uterine horns in estrogen-primed and pregnant mice.

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1.

Developmental changes in cerebellar endothelin-1 receptors in the neurologic mouse lurcher mutant.

Impaired ventilatory responses to hypoxia and hypercapnia in mutant mice deficient in endothelin-1.

Endothelin stimulates phospholipase D in striatal astrocytes.

Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice.

A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme.