GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
PMID:10627486
Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system.
PMID:10652215
Investigation of Fanconi anemia protein interactions by yeast two-hybrid analysis.
PMID:11063725
The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG.
PMID:11726552
Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.
PMID:12571280
Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links.
PMID:12649160
Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems.
PMID:16189514
Towards a proteome-scale map of the human protein-protein interaction network.
PMID:17289582
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
PMID:17396147
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway.
PMID:17474147
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.
PMID:19965384
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.
PMID:20347428
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
PMID:22266823
Regulation of Rev1 by the Fanconi anemia core complex.
PMID:22343915
FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway.
PMID:22705371
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.
PMID:22194614
Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms.
PMID:30057198
FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:37398436
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
PMID:8896564
Positional cloning of the Fanconi anaemia group A gene.
PMID:9398857
The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex.
Reactome:R-HSA-6785126
FA core complex assembles at DNA interstrand crosslinks (ICLs)
Reactome:R-HSA-6785342
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex
Reactome:R-HSA-6785361
Monoubiquitination of FANCD2:FANCI
Reactome:R-HSA-6785732
DNA nucleases bind monoubiquitinated ID2 complex
Reactome:R-HSA-6785986
DNA nucleases unhook the interstrand crosslink (ICL)
Reactome:R-HSA-6786155
POLN binds ICL-DNA
Reactome:R-HSA-6786166
Translesion synthesis across unhooked ICL by POLN
Reactome:R-HSA-6786171
FANCD2 deubiquitination by USP1:WDR48
Reactome:R-HSA-6788385
The complex of ATR and ATRIP is recruited to ICL-DNA
Reactome:R-HSA-6788392
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
Reactome:R-HSA-9835411
FA core complex:HSP70s binds PKR