Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
The Shq1p.Naf1p complex is required for box H/ACA small nucleolar ribonucleoprotein particle biogenesis.
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Shq1 and Naf1 are required for H/ACA snoRNP biogenesis and Shq1 interacts with Cbf5/Nhp2 assembly factors.
"The Shq1p.Naf1p complex is required for box H/ACA small nucleolar ribonucleoprotein particle biogenesis."
The box H/ACA snoRNP assembly factor Shq1p is a chaperone protein homologous to Hsp90 cochaperones that binds to the Cbf5p enzyme.
The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation.
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Oxygen-regulated localization data support both nuclear and cytosolic localization contexts for Shq1.
"over 120 nuclear proteins with important functions ranging from transcriptional regulation to RNA processing exhibit altered cellular locations under hypoxia"
Falcon deep research report on SHQ1
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Falcon synthesis identifies Shq1 as a conserved Cbf5 chaperone and RNA mimic required for H/ACA snoRNP assembly.
"SHQ1 encodes an essential assembly chaperone for box H/ACA small nucleolar/small Cajal body ribonucleoproteins."
PANTHER family PTHR12967 metadata