GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods.
PMID:10888872
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.
PMID:15161933
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
PMID:16357870
The Polycomb group protein EZH2 directly controls DNA methylation.
PMID:16791210
Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins.
PMID:16983096
Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA.
PMID:17673620
UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
PMID:17934516
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression.
PMID:17972916
RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes.
PMID:18413740
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.
PMID:18754681
CXXC domain of human DNMT1 is essential for enzymatic activity.
PMID:19282482
Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells.
PMID:19450230
SUMOylation enhances DNA methyltransferase 1 activity.
PMID:19798101
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.
PMID:20820192
BRCA1 affects global DNA methylation through regulation of DNMT1.
PMID:21151116
A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.
PMID:21653829
Protein interactome reveals converging molecular pathways among autism disorders.
PMID:21745816
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.
PMID:21947282
SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities.
PMID:22094255
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands.
PMID:24492612
Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.
PMID:24623306
A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype.
PMID:25544563
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.
PMID:25753001
A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells.
PMID:27021683
MiR-140-5p regulates hypoxia-mediated human pulmonary artery smooth muscle cell proliferation, apoptosis and differentiation by targeting Dnmt1 and promoting SOD2 expression.
PMID:27728808
Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for Cancer.
PMID:29691401
Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4(DCAF5) ubiquitin ligase.
PMID:32051553
The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:8940105
New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase.
Reactome:R-HSA-212222
PRC2 recruits DNA methyltransferases
Reactome:R-HSA-212269
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3
Reactome:R-HSA-4655431
SUMOyation of DNMT1 with SUMO1
Reactome:R-HSA-9710490
The GSDME gene promoter is hypermethylated
Reactome:R-HSA-9851058
AcK685 p-Y705, S727 STAT3 dimer and DNMT1 bind IL2RG gene
Reactome:R-HSA-9851071
STAT3, DNMT1 and HDAC1 bind PTPN6 gene
Reactome:R-HSA-9851145
Translation of DNMT1 mRNA is repressed by miR-21
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
PMID:12145218
Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases.
PMID:26070743
Crystal Structure of Human DNA Methyltransferase 1.
PMID:29053958
Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance.
PMID:21163962
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
PMID:36414620
Structural basis for activation of DNMT1.
PMID:20548288
Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice.
PMID:20573698
Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1.
PMID:21980460
Gestational exposure to low dose bisphenol A alters social behavior in juvenile mice.
PMID:25686699
LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration.
PMID:10615135
DNA methyltransferase Dnmt1 associates with histone deacetylase activity.
PMID:15220328
Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern.