Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies.

Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein.

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

Six3 and Six6 activity is modulated by members of the groucho family.

Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors.

Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma.

Absence of SIX6 mutations in microphthalmia, anophthalmia, and coloboma.

Homozygous truncation of SIX6 causes complex microphthalmia in humans.