Global alignment of cached UniProt sequences gives 527/541 identical paired residues (97.4%). Paired coverage is 94.4% of human P10809 (573 aa) and 100.0% of horse F6Z587 (541 aa).
Reproduce from the repository root with uv run python genes/HORSE/HSPD1/HSPD1-bioinformatics/align.py (Biopython). The full alignment is in alignment.txt; sequence hashes and scoring parameters are in results.json.
This measures conservation between the identified records. It is not a reciprocal orthology analysis and does not itself validate a functional annotation. Interpret it alongside locus identifiers, domain architecture and primary literature. The sequences are current cached UniProt records, not independently recovered prediction-time inputs.
These mappings report sequence conservation only; they do not validate targeting, activity or annotation transfer.
| Human feature | Human positions | Paired horse positions | Identical / paired |
|---|---|---|---|
| TRANSIT | 1–26 | 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26 | 20/26 |
| BINDING | 75–75 | 75 | 1/1 |
| BINDING | 111–115 | 111,112,113,114,115 | 5/5 |
| BINDING | 440–440 | 408 | 1/1 |
| BINDING | 520–520 | 488 | 1/1 |