Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Identification of a novel testis-specific leucine-rich protein in humans and mice.

Loss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesia.

LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects.

ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6.

Mutations in ZMYND10, a gene essential for proper axonemal assembly of inner and outer dynein arms in humans and flies, cause primary ciliary dyskinesia.

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms.

A reference map of the human binary protein interactome.

The effect of a novel LRRC6 mutation on the flagellar ultrastructure in a primary ciliary dyskinesia patient.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.

A liquid-like organelle at the root of motile ciliopathy.

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins.

LRRC6 regulates biogenesis of motile cilia by aiding FOXJ1 translocation into the nucleus.

DNAAF11 source guide and assay scope