GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:12397359
Dec1 and Dec2 are regulators of the mammalian molecular clock.
PMID:14672706
A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation.
PMID:15147242
Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system.
PMID:17463251
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.
PMID:20852621
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis.
PMID:21613214
Biochemical analysis of the canonical model for the mammalian circadian clock.
PMID:21680841
A molecular mechanism for circadian clock negative feedback.
PMID:22170608
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.
PMID:23133559
Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene.
PMID:26431207
CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:30530698
Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:8909283
Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.
PMID:9383998
Human blue-light photoreceptor hCRY2 specifically interacts with protein serine/threonine phosphatase 5 and modulates its activity.
PMID:9801304
Characterization of photolyase/blue-light receptor homologs in mouse and human cells.