flbA (Aspergillus nidulans) — curation notes
UniProt P38093 (FLBA_EMENI). RGS protein; repressive gating tier (attenuates FadA).
- RGS domain protein antagonizing FadA to block proliferation and allow development. PMID:8895563. Overexpression activates brlA prematurely PMID:7830576.
- Core MF GO:0005096 GTPase activator activity. GO:0045461 ST biosynthetic process over-annotation; GO:0045574 sterigmatocystin catabolic process flagged likely-spurious (contradicts FlbA's positive-regulatory role in ST biosynthesis).
Re-review 2026-10-01 (GOA refresh)
- No new GOA rows and no vanished rows for flbA in the refreshed snapshot.
- GO:0045574 sterigmatocystin catabolic process (IMP, PMID:9339347): changed
MARK_AS_OVER_ANNOTATED -> UNDECIDED. The earlier "likely curation artifact"
call second-guessed an experimental annotation whose paper is cached as abstract
only; the abstract does not let us see what the curator read, so the row is left
undecided rather than overruled.