Human PRC1 purification resolved different PCGF-containing assemblies, including AUTS2-associated PCGF3/5 complexes. Selected chromatin-compaction experiments concern PRC1.4 and do not establish a uniform compaction role for every AUTS2 complex.

Human AUTS2 reporter and reconstitution experiments support recruitment of P300 and CK2. PCGF5 bridges the tested RING1B association; the recruited enzymes supply acetylation and phosphorylation. Mouse CNS chromatin and developmental experiments provide distinct physiological evidence.

Human affinity-purification mass spectrometry maps Polycomb assemblies. Exact AUTS2-PCGF5 and AUTS2-RNF2 experiment records have not been inspected.

BioPlex 2.0 profiles human protein co-associations by affinity purification and mass spectrometry. Its exact AUTS2-PCGF5 record remains uninspected.

BioPlex 3.0 compares protein interaction networks in human 293T and HCT116 cells. The exact AUTS2-PCGF5 pair and relevant assay configuration remain unresolved.

Human HX-repeat variants impair P300 association and transcriptional activation while retaining RING1B association. P300 recruitment and reporter activation depend on PCGF3/5. Separate mouse brain and neural-differentiation experiments show NRF1 association and NRF1-dependent recruitment of AUTS2-containing ncPRC1.3. Mouse homozygous perturbations do not directly reproduce heterozygous human disease.

Mouse neuronal and cell-based loss-of-function/rescue experiments support a cytoplasmic AUTS2 pathway affecting Rac1/Cdc42 signaling, actin-based protrusions, neuronal migration and neurite growth. This pathway association does not assign nucleotide-exchange catalysis to AUTS2 or establish the same experiment in human neurons.

Long and short AUTS2 constructs have different, context-dependent transcriptional effects and interaction profiles. Human transcripts rescue survival defects in mouse embryonic stem-cell differentiation experiments. Experimental long/short labels do not uniquely identify all four natural human UniProt products.

This record is a published erratum linked to the original NRF1/AUTS2 study, DOI 10.1016/j.molcel.2021.09.020. It supplies no scientific abstract or additional experimental evidence. The separately consulted correction notice concerns authorship, contributions and funding.