Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Electronic Gene Ontology annotations created by ARBA machine learning models
Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16.
Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence.
A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway.
Androgen receptor auto-regulates its expression by a negative feedback loop through upregulation of IFI16 protein.
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.
Defining the membrane proteome of NK cells.
IFI16 is an innate immune sensor for intracellular DNA.
A diverse range of gene products are effectors of the type I interferon antiviral response.
IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway.
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.
IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes.
The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines.
The human interferon-inducible protein, IFI 16, is a repressor of transcription.
The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations.
IFI16 binds cytosolic dsDNA